Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin

J Dong, Y Gong, J Liu, X Chen, X Wen, H Sun

Index: Bioorganic and Medicinal Chemistry, , vol. 22, # 4 p. 1383 - 1393

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Citation Number: 5

Abstract

... Bioorganic & Medicinal Chemistry. ... Moreover, as potential impurities of saxagliptin API (Active Pharmaceutical Ingredient), the synthesis of stereoisomers 1b–1h is highly desirable to provide the reference substances for drug quality control. ...

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