Silicon-containing dipeptidic aspartame and neotame analogues

…, S Falgner, S Schweeberg, C Burschka…

Index: Barnes, Matthew J.; Burschka, Christian; Buettner, Matthias W.; Conroy, Richard; Daiss, Juergen O.; Gray, Ian C.; Hendrick, Alan G.; Tam; Kuehn, Diana; Miller, David J.; Mills, John S.; Mitchell, Philip; Montana, John G.; Muniandy, Parameswary A.; Rapley, Helen; Showell, Graham A.; Tebbe, David; Tacke, Reinhold; Warneck, Julie B.H.; Zhu, Bin ChemMedChem, 2011 , vol. 6, # 11 p. 2070 - 2080

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Citation Number: 5

Abstract

A series of seven silicon-containing dipeptides ((S, R)-5,(S, S)-5,(S, R)-6,(S, R)-7,(S, S)-7,(S, R)-8, and (S, S)-8) was prepared in multistep syntheses, starting from the enantiopure silicon- containing α-methylated α-amino acids (R)-or (S)-α-[(trimethylsilyl) methyl] alanine ((R)-4 or

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