Tetrahedron

N-Alkylation of poor nucleophilic amines and derivatives with alcohols by a hydrogen autotransfer process catalyzed by copper (II) acetate: scope and mechanistic …

A Martínez-Asencio, DJ Ramón, M Yus

Index: Martinez-Asencio, Ana; Ramon, Diego J.; Yus, Miguel Tetrahedron, 2011 , vol. 67, # 17 p. 3140 - 3149

Full Text: HTML

Citation Number: 71

Abstract

Copper (II) acetate is a versatile, cheap and simple catalyst for the selective N- monoalkylation of amino derivatives with poor nucleophilic character, such as aromatic and heteroaromatic amines as well as carboxamides, phosphinamides, sulfonamides, and phosphazenes, using in all cases primary alcohols as initial source of the electrophiles, through a hydrogen autotransfer process. In the case of sulfonamides, the monoalkylation ...

Related Articles:

Reduction of azides to amines mediated by tin bis (1, 2-benzenedithiolate)

[Bosch, Imma; Costa, Anna M.; Martin, Manuel; Urpi, Felix; Vilarrasa, Jaume Organic Letters, 2000 , vol. 2, # 3 p. 397 - 399]

Pd black deposited on polypropylene sheet as a highly selective catalyst for hydrogenation of alkenes

[Maki, Shojiro; Okawa, Makiko; Makii, Toshimichi; Hirano, Takashi; Niwa, Haruki Tetrahedron Letters, 2003 , vol. 44, # 18 p. 3717 - 3721]

Weak Interactions Dominating the Supramolecular Self-Assembly in a Salt: A Designed Single-Crystal-to-Single-Crystal Topochemical Polymerization of a Terminal …

[Vidya Sagar Reddy; Venkat Rao; Subramanyam; Iyengar Synthetic Communications, 2000 , vol. 30, # 12 p. 2233 - 2237]

Direct hydrogenation of amides to alcohols and amines under mild conditions

[Journal of the American Chemical Society, , vol. 132, # 47 p. 16756 - 16758]

A New and Convenient Method for Reduction of Oximes to Amines with NaBH 3 CN In the Presence of MoCl 5/NaHSO 4· H 2 O System

[Kouhkan, Mehri; Zeynizadeh, Behzad Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 9 p. 3323 - 3326]

More Articles...