Synthesis and pharmacology of 3, 4-dihydro-3-oxo-1, 4-benzoxazine-8-carboxamide derivatives, a new class of potent serotonin-3 (5-HT3) receptor antagonists.

川北武志， 黒板孝信， 安本光由， 佐野光春…

Index: Chemical and Pharmaceutical Bulletin, , vol. 40, # 3 p. 624 - 630

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Citation Number: 32

Abstract

... Chemistry Compounds 9 and 12—26 were prepared as shown in Chart 3. The ... spectra were recorded on a JEOL PS-100 spectrometer and the chemical shifts are ... Elemental analysis and measurement of these spectra were performed by Yoshitomi Pharmaceutical Industries, Ltd ...