Preparation of oxygenated phenylacetic acids
…, EP Stirchak, A Yokoyama
Index: Weller, Dwight D.; Stirchak, Eugene P.; Yokoyama, Ayumu Journal of Organic Chemistry, 1984 , vol. 49, # 11 p. 2061 - 2063
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Citation Number: 22
Abstract
Oxygen-substituted phenylacetic acids have been employed in the synthesis of a wide variety of natural products, embracing such diverse species as flavonoids and alkaloids.'p2 One especially important area is their use in the synthesis of the opiate alkaloid^.^^^ Rice has employed (3-hydroxy-4-methoxypheny1) acetic acid (1, homoisovanillic acid) in a concise synthesis of the opiate precursor dihydrothebainone.% d In a related approach to ...
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