Tetrahedron letters

Facile reduction of tertiary lactams to cyclic amines with 9-borabicyclo [3.3. 1] nonane (9-BBN)

CJ Collins, M Lanz, B Singaram

Index: Collins, Christopher J.; Lanz, Marc; Singaram, Bakthan Tetrahedron Letters, 1999 , vol. 40, # 19 p. 3673 - 3676

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Citation Number: 30

Abstract

Various 5-and 6-membered tertiary lactams were reduced to the corresponding cyclic tertiary amines using 2.2 to 2.5 equivalents of 9-borabicyclo [3.3. 1] nonane (9-BBN). This method is highly chemoselective and it is easy to reduce a lactam in the presence of an ester.

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