A Safe and Efficient Route for the Preparation of Nitro-, Dinitro-, and Trinitrophenyl Chloroformates

…, V Pejchal, A Imramovský, J Hanusek

Index: Sedlak, Milos; Pejchal, Vladimir; Imramovsky, Ales; Hanusek, Jiri Synthetic Communications, 2013 , vol. 43, # 17 p. 2365 - 2369

Full Text: HTML

Citation Number: 0

Abstract

A safe and simple method has been developed for synthesis of chloroformates derived from 2-nitrophenol, 4-nitrophenol, 2,4-dinitrophenol, 2,4,6-trinitrophenol, and pentafluorophenol, the yields being in the range of 72–96%. The method is based on a heterogeneous reaction of the substituted phenol with phosgene dissolved in dichloromethane catalyzed with solid anhydrous potassium carbonate. The synthesis of 2,4,6-trinitrophenyl chloroformate takes place only ...