Synthesis and immunomodulatory properties of selected oxazolone derivatives

…, MI Choudhary, S Murad, Z Ismail, A Ahmad

Index: Mesaik, Muhammad A.; Rahat, Shagufta; Khan, Khalid M.; Zia-Ullah; Choudhary, Muhammad I.; Murad, Shahnaz; Ismail, Zakiah; Atta-ur-Rahman; Ahmad, Aqeel Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 9 p. 2049 - 2057

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Citation Number: 59

Abstract

Eleven oxazolone derivatives were synthesized and characterized by 1H NMR, EI, IR and UV spectroscopic and CHN analysis. Three compounds, 4-[(E)-(4-nitrophenyl) methylidene]- 2-phenyl-1, 3-oxazol-5 (4H)-one (11), 4-[(E)-(4-methoxyphenyl) methylidene]-2-methyl-1, 3- oxazol-5-one (12) and 4-[(E)-(4-nitrophenyl) methylidene]-2-methyl-1, 3-oxazol-5 (4H)-one (13) were screened for phagocyte chemiluminescence, neutrophil chemotaxis, T-cell ...

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