Synthesis of exaltone and dl-muscone based on 1, 5, 9-cyclododecatriene

H Nozaki, H Yamamoto, T Mori

Index: Nozaki,H. et al. Canadian Journal of Chemistry, 1969 , vol. 47, p. 1107 - 1112

Full Text: HTML

Citation Number: 28

Abstract

Bicyclo [941] hexadecan-16-one is prepared from cyclododecanone via four steps: ethoxycarbonylation, condensation with 1, 4-dibromobutane, saponification, and decarboxylation. Photolysis of the bicyclic ketone yields a ketene which is trapped with methanol to afford methyl cyclopentadecanecarboxylate or alternatively oxidized to exaltone directly. The ester is also converted into exaltone via five steps. dl-Muscone is prepared by ...