Tetrahedron letters

One pot conversion of alkyl halides into thiols under mild conditions

P Molina, M Alajarin, MJ Vilaplana, AR Katritzky

Index: Molina, P.; Alajarin, M.; Vilaplana, M. J.; Katritzky, A. R. Tetrahedron Letters, 1985 , vol. 26, # 4 p. 469 - 472

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Citation Number: 18

Abstract

Experimental for the preparation of : Ethanolamine (3.66 g, 60 mmol) was added to 4,6-diphenyl-2H-pyran-2-thione (13.2 g, 50 (mmol) in boiling methanol (250 ml) and the resulting mixture was heated at reflux for 5 h. After cooling volatiles were removed under reduced pressure and the residual material was thoroughly washed with water, dried under vacuum and the crude pyridine-2-thione (12.75 g, 83%) thus obtained was used without further purification in the ...

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