Convenient synthesis and transformation of 2, 6-dichloro-4-iodopyridine

JV Mello, NS Finney

Index: Mello, Jesse V.; Finney, Nathaniel S. Organic Letters, 2001 , vol. 3, # 26 p. 4263 - 4265

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Citation Number: 33

Abstract

In the course of extending our work on arylpyridine fluorescent chemosensors, 1 we required ready access to 2,4,6-trisubstituted pyridines. While such compounds can be prepared by any of a number of condensation methods, 2,3 we were drawn to the comparative simplicity and convergence of directly installing the substituents via transition metal catalyzed coupling to a pyridine precursor. The dearth of procedures for the preparation of appropriate trihalopyridines ...