Regioisomerism in the Synthesis of a Chiral Aminotetralin Drug Compound: Unraveling Mechanistic Details and Diastereomer-Specific In-Depth NMR Investigations

P Schuisky, HJ Federsel, W Tian

Index: Miyano, Sotaro; Fukushima, Hiroshi; Inagawa, Hideho; Hashimoto, Harukichi Bulletin of the Chemical Society of Japan, 1986 , vol. 59, p. 3285 - 3286

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Citation Number: 3

Abstract

... 10.1021/jo300277y. Publication Date (Web): June 4, 2012. Copyright © 2012 American Chemical Society. ... prepared using a synthetic route devised by the medicinal chemistry team.(4 ... converted to an (R)-aminotetralin derivative ready for further chemical manipulations (Scheme 1 ...