Discovery and early clinical evaluation of BMS-605339, a potent and orally efficacious tripeptidic acylsulfonamide NS3 protease inhibitor for the treatment of hepatitis …

PM Scola, AX Wang, AC Good, LQ Sun…

Index: Journal of Medicinal Chemistry, , vol. 57, # 5 p. 1708 - 1729

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Citation Number: 22

Abstract

... Journal of Medicinal Chemistry. ... are less than 50%. Hence, in the development of direct acting antivirals, the GT-1 virus has been a primary focus of efforts due to the more acute medical need. As a consequence of ...