Copper (II) acetate mediated conversion of ortho aminomethyl substituted isoquinolines to bis (isoquinolylcarbonyl) amides

R Sahu, VK Fulwa, HS Jena, V Manivannan

Index: Sahu, Rojalin; Fulwa, Vijendra Kumar; Jena, Himanshu Sekhar; Manivannan, Vadivelu Polyhedron, 2012 , vol. 33, # 1 p. 9 - 12

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Citation Number: 3

Abstract

An ethanolic solution of ortho aminomethyl substituted isoquinolines, on stirring in air with half equivalent of [Cu (OAc) 2 (H2O)], afforded [Cu (1-L)(OAc)](1) and [Cu (3-L)(OAc)](2){1- L= bis (1-isoquinolylcarbonyl) amide ion and 3-L= bis (3-isoquinolylcarbonyl) amide ion}. This reaction involves the oxidation of a methylene group and the formation of a bond between nitrogen and carbon in N–C (O) through coupling. The free ligands can be ...