A simple general approach to phenanthridinones via palladium-catalyzed intramolecular direct arene arylation
R Bernini, S Cacchi, G Fabrizi, A Sferrazza
Index: Bernini, Roberta; Cacchi, Sandro; Fabrizi, Giancarlo; Sferrazza, Alessio Synthesis, 2008 , # 5 p. 729 - 738
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Citation Number: 13
Abstract
Known palladium-catalyzed approaches to the construction of the phenanthridinone frame are based on the intramolecular cyclization of N-(o-halobenzoyl)- or N-(o-triflyloxybenzoyl)anilides , [7] a domino process (including aryl-aryl coupling between two o-bromobenzamide units and CN bond formations concomitant with a deamidation reaction), [8] a one-pot consecutive aryl-aryl and N-aryl coupling from iodoarenes bearing ortho electron-releasing ...
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