Amino acids

Towards non-peptide ANG II AT1 receptor antagonists based on urocanic acid: rational design, synthesis and biological evaluation

G Agelis, A Resvani, MT Matsoukas, T Tselios…

Index: Amino Acids, , vol. 40, # 2 p. 411 - 420

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Citation Number: 6

Abstract

... 6). The main amino acids participating in hydrogen bond interactions were S3.33(109), L(191), N5 ... derivatives 11a–c as potential ANG II AT1 receptor antagonists, based on urocanic acid. ... for binding in AT1 receptor antagonists (2) the smaller molecular weight and volume of our ...

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