Tetrahedron letters

Pummerer reaction methodology for the synthesis of 5-thiophenyl substituted oxazoles

JD Kreisberg, P Magnus, S Shinde

Index: Kreisberg, Jennifer D; Magnus, Philip; Shinde, Shirin Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7393 - 7396

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Citation Number: 24

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Treatment of N-acylamino-2-thiophenyl derivatives with N-chlorosuccinimide (2.0 equiv.) followed by SnCl 4 (0.1–1.0 equiv.) provides a direct synthesis of 5-thiophenyloxazoles. ... Treatment of 1 with NCS, followed by SnCl 4 results in the formation of 5-thiophenyloxazoles 2.

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