Synthesis

New convergent synthesis of carbocyclic nucleoside analogues

OR Ludek, C Meier

Index: Ludek, Olaf R.; Meier, Chris Synthesis, 2003 , # 13 p. 2101 - 2109

Full Text: HTML

Citation Number: 37

Abstract

Abstract Two convergent approaches towards the synthesis of carbocyclic nucleoside analogs will be described. Both approaches start from the stereochemically pure cyclopentenol 8 that has been prepared enantioselectively from an alkylated cyclopentadiene. Using these approaches, carbocyclic analogues of dT, FdU and BVdU have been prepared. Moreover, the conversion into the cycloSal-pronucleotide and the ...

Related Articles:

The first stereospecific synthesis of (+)-(1r, 2s, 4r)-4-amino-2-hydroxy-1-cyclopentanemethanol and (+)-carbocyclic thymidine.

[Otvos; Beres; Sagi; Tomoskozi; Gruber Tetrahedron Letters, 1987 , vol. 28, # 50 p. 6381-6384]

The first stereospecific synthesis of (+)-(1r, 2s, 4r)-4-amino-2-hydroxy-1-cyclopentanemethanol and (+)-carbocyclic thymidine.

[Otvos; Beres; Sagi; Tomoskozi; Gruber Tetrahedron Letters, 1987 , vol. 28, # 50 p. 6381-6384]

The first stereospecific synthesis of (+)-(1r, 2s, 4r)-4-amino-2-hydroxy-1-cyclopentanemethanol and (+)-carbocyclic thymidine.

[Otvos; Beres; Sagi; Tomoskozi; Gruber Tetrahedron Letters, 1987 , vol. 28, # 50 p. 6381-6384]

The first stereospecific synthesis of (+)-(1r, 2s, 4r)-4-amino-2-hydroxy-1-cyclopentanemethanol and (+)-carbocyclic thymidine.

[Otvos; Beres; Sagi; Tomoskozi; Gruber Tetrahedron Letters, 1987 , vol. 28, # 50 p. 6381-6384]

The first stereospecific synthesis of (+)-(1r, 2s, 4r)-4-amino-2-hydroxy-1-cyclopentanemethanol and (+)-carbocyclic thymidine.

[Otvos; Beres; Sagi; Tomoskozi; Gruber Tetrahedron Letters, 1987 , vol. 28, # 50 p. 6381-6384]

More Articles...