Tetrahedron

Insights into the bromination of 3-aryl-5-methyl-isoxazole-4-carboxylate: synthesis of 3-aryl-5-bromomethyl-isoxazole-4-carboxylate as precursor to 3-aryl-5-formyl- …

AK Roy, B Rajaraman, S Batra

Index: Roy, Amrendra K.; Rajaraman; Batra, Sanjay Tetrahedron, 2004 , vol. 60, # 10 p. 2301 - 2310

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Citation Number: 12

Abstract

Results of the detailed investigations on the bromination of the methyl group of 3-aryl-5- methyl-isoxazole-4-carboxylate, a precursor to obtain 3-aryl-5-formyl-isoxazole-4- carboxylate, are described. The products generated during the study have been utilized as substrates for the synthesis of isoxazole-fused heterocycles.