A high speed parallel synthesis of 1, 2-diaryl-1-ethanones via a clean-chemistry C–C bond formation reaction

VR Veeramaneni, M Pal, KR Yeleswarapu

Index: Veeramaneni, Venugopal Rao; Pal, Manojit; Yeleswarapu, Koteswar Rao Tetrahedron, 2003 , vol. 59, # 18 p. 3283 - 3290

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Citation Number: 42

Abstract

In this report, we describe the parallel as well as conventional synthesis of 1, 2-diaryl-1- ethanones via environmentally benign acylation of arenes with in situ generated arylacetyl trifluoroacetates. A wide variety of arylacetic acids I participated in trifluoroacetic anhydride/phosphoric acid mediated C–C bond formation reaction when reacted with arenes of type II to give 1, 2-diaryl-1-ethanones III in good to excellent yield. Under the ...