New and effective routes to fluoro analogs of aliphatic and aromatic amino acids

…, K Nakahashi, T Fuchikami, M Fujita

Index: Ojima, Iwao; Kato, Koji; Nakahashi, Kazuaki; Fuchikami, Takamasa; Fujita, Makoto Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4511 - 4522

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Citation Number: 108

Abstract

Trifluorovaline (1) and trifluoronorvaline (2) are synthesized through amidocarbonylation of 2-(trifluoromethy1) propanal (2-TFMPA) and 3-(trifluoromethyl) propanal (3-TFMPA), respectively, followed by hydrolysis. Trifluoroleucine (5) and trifluoronorleucine (6) are ...