Bi (CF 3) 3/Cu (OCOCH 3) 2—a new system for the synthesis of 2-trifluoromethylcycloalkan-1-ones, trifluoromethylanilines and phenyl (trifluoromethyl) sulfane

NV Kirij, SV Pasenok, YL Yagupolskii, W Tyrra…

Index: Kirij; Pasenok; Yagupolskii; Tyrra; Naumann Journal of Fluorine Chemistry, 2000 , vol. 106, # 2 p. 217 - 221

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Citation Number: 17

Abstract

Bi (CF3) 3 reacts in the presence of equimolar amounts of Cu (OCOCH3) 2 and 1- morpholinocyclopentene to give 1-morpholino-2-trifluoromethylcyclopentene in 83% yield. This compound as well as intermediately formed 1-morpholino-2-trifluoromethylcyclohexene can easily be converted into the corresponding cycloketones (78 and 41% yield) using the Swarts procedure. In absence of a copper (II) source, no reactions were observed. The ...