FeCl 3-catalysed ultrasonic-assisted, solvent-free synthesis of 4-substituted coumarins. A useful complement to the Pechmann reaction

…, N Avlonitis, GA Heropoulos, T Calogeropoulou

Index: Prousis, Kyriakos C.; Avlonitis, Nicolaos; Heropoulos, Georgios A.; Calogeropoulou, Theodora Ultrasonics Sonochemistry, 2014 , vol. 21, # 3 p. 937 - 942

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Citation Number: 10

Abstract

Abstract The catalytic activity of FeCl 3 for the synthesis of a variety of 4-substituted coumarins using high energy techniques has been investigated. The ultrasonic-assisted conditions provide a useful complement to the Pechmann reaction, affording the coumarin derivatives in excellent yields, under solvent-free conditions, in short reaction times using an inexpensive, mild and benign Lewis acid catalyst.

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