Discovery and SAR development of 2-(phenylamino) imidazolines as postacyclin receptor antagonists

RD Clark, A Jahangir, D Severance, R Salazar…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 4 p. 1053 - 1056

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Citation Number: 52

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... a Department of Medicinal Chemistry, Roche Palo ... 1α have been found in inflammatory exudates, for example from synovial fluid from human arthritic knee joints 2 and from the peritoneal cavity fluid of mice injected with chemical irritants ...