Tetrahedron

Direct synthesis of 3-arylpropionic acids by tetraphosphine/palladium catalysed Heck reactions of aryl halides with acrolein ethylene acetal

M Lemhadri, H Doucet, M Santelli

Index: Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540

Full Text: HTML

Citation Number: 30

Abstract

Through the use of [PdCl (C3H5)] 2/Cis, cis, cis-1, 2, 3, 4-tetrakis (diphenylphosphinomethyl) cyclopentane as a catalyst, a range of aryl bromides undergoes Heck reaction with acrolein ethylene acetal. With this acetal, the selective formation of 3-arylpropionic acids/esters was observed. The functional group tolerance on the aryl halide is remarkable; substituents such as fluoro, methyl, methoxy, acetyl, formyl, benzoyl, nitro or nitrile are tolerated. ...

Related Articles:

Dirhodium (II) carboxylate complexes as building blocks. Cis-chelating dicarboxylic acids designed to bridge the dinuclear core

[Bickley, Jamie; Bonar-Law, Richard; McGrath, Thomas; Singh, Nirmal; Steiner, Alexander New Journal of Chemistry, 2004 , vol. 28, # 3 p. 425 - 433]

Ein neuer Weg in die Bicyclo [3.3. 1] nonan??und Bicyclo [3.2. 1] octan??Reihe

[Buchta,E.; Billenstein,S. Justus Liebigs Annalen der Chemie, 1966 , vol. 692, p. 42 - 52]

Ein neuer Weg in die Bicyclo [3.3. 1] nonan??und Bicyclo [3.2. 1] octan??Reihe

[Buchta,E.; Billenstein,S. Justus Liebigs Annalen der Chemie, 1966 , vol. 692, p. 42 - 52]

Ein neuer Weg in die Bicyclo [3.3. 1] nonan??und Bicyclo [3.2. 1] octan??Reihe

[Buchta,E.; Billenstein,S. Justus Liebigs Annalen der Chemie, 1966 , vol. 692, p. 42 - 52]

Dirhodium (II) carboxylate complexes as building blocks. Cis-chelating dicarboxylic acids designed to bridge the dinuclear core

[Bickley, Jamie; Bonar-Law, Richard; McGrath, Thomas; Singh, Nirmal; Steiner, Alexander New Journal of Chemistry, 2004 , vol. 28, # 3 p. 425 - 433]

More Articles...