Synthesis

Improved procedure for palladium-catalyzed Hiyama cross-coupling reaction of aryl halides with aryltrimethoxysilanes under solvent-free conditions

JH Li, CL Deng, YX Xie

Index: Li, Jin-Heng; Deng, Chen-Liang; Xie, Ye-Xiang Synthesis, 2006 , # 6 p. 969 - 974

Full Text: HTML

Citation Number: 18

Abstract

Abstract An improved palladium-catalyzed Hiyama cross-coupling reaction is reported. In the presence of PdCl 2 (MeCN) 2, P (o-tol) 3 and TBAF, a number of ArX (X= I, Br, Cl) were coupled with ArSi (OMe) 3 efficiently to afford the desired cross-coupled products in moderate to excellent yields. It is noteworthy that this protocol is conducted under relatively low Pd loadings and solvent-free conditions.

Related Articles:

NHC–Pd (II)–Im (NHC= N-heterocyclic carbene; Im= 1-methylimidazole) complexes as efficient catalysts for Suzuki-Miyaura coupling reactions of aryl chlorides

[Tang, Yi-Qiang; Lu, Jian-Mei; Shao, Li-Xiong Journal of Organometallic Chemistry, 2011 , vol. 696, # 23 p. 3741 - 3744]

Ligand-free, atom-efficient Suzuki–Miyaura type cross-coupling reactions at room temperature

[Zhou, Wen-Jun; Wang, Ke-Hu; Wang, Jin-Xian; Gao, Zhi-Rong Tetrahedron, 2010 , vol. 66, # 38 p. 7633 - 7641]

Monodispersed and Stable Nano Copper (0) from Copper??Aluminium Hydrotalcite: Importance in C C Couplings of Deactivated Aryl Chlorides

[Arundhathi, Racha; Damodara, Dandu; Mohan, Kakita Veera; Kantam, Mannepalli Lakshmi; Likhar, Pravin R. Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 751 - 756]

Direct catalytic cross-coupling of organolithium compounds

[Giannerini, Massimo; Fananas-Mastral, Martin; Feringa, Ben L. Nature Chemistry, 2013 , vol. 5, # 8 p. 667 - 672]

A base-free, one-pot diazotization/cross-coupling of anilines with arylboronic acids

[Mo, Fanyang; Qiu, Di; Jiang, Yubo; Zhang, Yan; Wang, Jianbo Tetrahedron Letters, 2011 , vol. 52, # 4 p. 518 - 522]

More Articles...