Metalloantimalarials: synthesis and characterization of a novel agent possessing activity against Plasmodium falciparum

JA Ocheskey, SE Harpstrite, A Oksman…

Index: Ocheskey, Joseph A.; Harpstrite, Scott E.; Oksman, Anna; Goldberg, Daniel E.; Sharma, Vijay Chemical Communications, 2005 , # 12 p. 1622 - 1624

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Citation Number: 15

Abstract

The synthesis, characterization, and antimalarial potency of an amine-phenol complex of gallium (III),[{1, 12-bis (2-hydroxy-3-methoxy-5-(quinolin-3-yl)-benzyl)-1, 5, 8, 12- tetraazadodecane}-gallium (III)]+,[Ga-3-M-5-Quadd]+(7) is described; a novel agent that targets Plasmodium falciparum strains.