An eco-friendly procedure for the efficient synthesis of bis (indolyl) methanes in aqueous media

…, E Safaei, AR Hasaninejad, S Rezazadeh

Index: Sobhani, Sara; Safaei, Elham; Hasaninejad, Ali-Reza; Rezazadeh, Soodabeh Journal of Organometallic Chemistry, 2009 , vol. 694, # 18 p. 3027 - 3031

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Citation Number: 42

Abstract

A new, convenient and high yielding procedure for the preparation of bis (indolyl) methanes in water by electrophilic substitution reaction of indoles with different carbonyl compounds in the presence of a catalytic amount of [Cu (3, 4-tmtppa)](MeSO4) 4 (1mol%) as a highly stable and reusable catalyst is described. This procedure has also been applied successfully for the preparation of bis (pyrazole-5-ols) and dipyrromethanes.