Nitrile biotransformation by whole cells of Aspergillus sp. PTCC 5266

…, M Mohammadi, Z Habibi, Z Cheraghi

Index: Yousefi; Mohammadi; Habibi; Cheraghi Biocatalysis and Biotransformation, 2011 , vol. 29, # 2-3 p. 54 - 59

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Citation Number: 3

Abstract

Abstract Aspergillus sp. PTCC 5266 exhibited nitrile-hydrating activity over a broad pH range from 6.0 to 10.0 at 26° C. It hydrated 4-nitrophenylacetonitrile, 2-chlorobenzonitrile and 3-chlorobenzonitrile to their corresponding carboxylic acids and amides, while benzyl cyanide, benzonitrile, 4-tolunitrile, cyclohexanecarbonitrile, 4-chlorobutyronitrile and isobutyronitrile gave carboxylic acids as the sole products. The maximum whole-cell nitrile ...