Discovery of a novel series of potent S1P1 agonists

S Crosignani, A Bombrun, D Covini, M Maio…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 5 p. 1516 - 1519

Full Text: HTML

Citation Number: 8

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 1). This compound was considered to be a suitable starting point for a medicinal chemistry program ... 2-chloropyrimidine intermediates 4 could also be used to prepare some 2-substituted compounds via either Pd-catalyzed chemistry or S ...