Cyclization of 2??and 3??indolythioalkanoic acids to novel indole??containing tricyclic ring systems

P Hamel, M Girard

Index: Hamel, Pierre; Girard, Mario Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1695 - 1701

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Citation Number: 8

Abstract

Abstract A series of 2-and 3-indolylthioalkanoic acids of various chain lengths were cyclized under dehydrative conditions affording tricyclic indole-containing ring systems wherein the third ring contains a sulfur atom attached to the 2-or 3-position of the indole ring. This methodology affords entry into the novel thiepino [3, 2-b] indole, thiocino [2, 3-b] indole and thiocino [3, 2-b] indole ring systems.