Efficient and Clean Gold??Catalyzed One??Pot Selective N??Alkylation of Amines with Alcohols

L He, XB Lou, J Ni, YM Liu, Y Cao…

Index: He, Lin; Lou, Xia-Bing; Ni, Ji; Liu, Yong-Mei; Cao, Yong; He, He-Yong; Fan, Kang-Nian Chemistry - A European Journal, 2010 , vol. 16, # 47 p. 13965 - 13969

Full Text: HTML

Citation Number: 104

Abstract

The N-alkylation of primary amines to secondary amines is of fundamental importance in organic synthesis, granting access to valuable N-alkylamines that are widely used as pharmacophores in numerous biologically active compounds, dyes, agrochemicals and functionalized materials.[1] The most commonly used method for N-alkylation is the coupling of amines with alkyl halides [2] in the presence of stoichiometric amounts of bases. This ...

Related Articles:

Catalytic hydrogenation of valeronitrile over Raney nickel. II, Reactivity of intermediates

[Bulletin de la Societe Chimique de France, , # 1 p. 13 - 19]

Hydrogenolysis of nitrogen-containing compounds on cobalt-molybdenum catalysts

[Collection of Czechoslovak Chemical Communications, , vol. 45, # 8 p. 2215 - 2218]

Reaction of Aliphatic Amines with 49% Formic Acid. 1??Hexylamine, di??1??hexylamine, N, N??dimethyl??1??hexylamine, 1??dodecylamine, N, N??dimethyl??1??dodecylamine …

[Journal fur Praktische Chemie - Chemiker - Zeitung, , vol. 339, # 1 p. 59 - 65]

Hydrogenolysis of nitrogen-containing compounds on cobalt-molybdenum catalysts

[Collection of Czechoslovak Chemical Communications, , vol. 45, # 8 p. 2215 - 2218]

N-alkyl-4-(N′, N′-dialkylamino) pyridinium salts: thermally stable phase transfer catalysts for nucleophilic aromatic displacement

[Tetrahedron Letters, , vol. 25, # 32 p. 3383 - 3386]

More Articles...