Tetrahedron letters

Radical mediated-direct conversion of aldehydes into acid bromides

DH Kang, TY Joo, W Chavasiri, DO Jang

Index: Kang, Dong Ho; Joo, Tae Young; Chavasiri, Warinthorn; Jang, Doo Ok Tetrahedron Letters, 2007 , vol. 48, # 2 p. 285 - 287

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Citation Number: 6

Abstract

A method of preparing acid bromides directly from aldehydes with Br3CCO2Et under radical conditions was developed. Aromatic aldehydes with electron-donating group were found to be more reactive than aromatic aldehydes with electron-withdrawing group and aliphatic aldehydes under reaction conditions.