Structure–activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents

…, K Shimura, M Matsuoka, S Okazaki, T Takeuchi…

Index: Mizuhara, Tsukasa; Kato, Takayuki; Hirai, Atsushi; Kurihara, Hideki; Shimada, Yasuhiro; Taniguchi, Masahiko; Maeta, Hideki; Togami, Hiroaki; Shimura, Kazuya; Matsuoka, Masao; Okazaki, Shiho; Takeuchi, Tomoki; Ohno, Hiroaki; Oishi, Shinya; Fujii, Nobutaka Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 16 p. 4557 - 4561

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Citation Number: 9

Abstract

Abstract The structure–activity relationship of phenylpyrazole derivative 1 was investigated for the development of novel anti-HIV agents. Initial efforts revealed that the diazenyl group can be replaced by an aminomethylene group. In addition, we synthesized various ...