The Influence of Boronate Groups on the Selectivity of the Br–Li Exchange in Model Dibromoaryl Boronates

…, J Smętek, M Dąbrowski, J Serwatowski…

Index: Durka, Krzysztof; Lulinski, Sergiusz; Smetek, Jaromir; Dabrowski, Marek; Serwatowski, Janusz; Wozniak, Krzysztof European Journal of Organic Chemistry, 2013 , # 15 p. 3023 - 3032

Full Text: HTML

Citation Number: 0

Abstract

Abstract The selectivity of the Br/Li exchange reaction of 6-butyl-2-(2, 5-dibromophenyl)-1, 3, 6, 2-dioxazaborocane (2, 5-Br 2 C 6 H 3 B (OCH 2 CH 2) 2 NBu) and the analogous anionic derivatives, 2, 5-Br 2 C 6 H 3 B (OiPr) 3 Li and 2, 5-Br 2 C 6 H 3 BF 3 K, was investigated using nBuLi as the lithiating reagent. In the case of the former compound there was a slight preference for lithiation at the 5-position. For 2, 5-Br 2 C 6 H 3 B (OiPr) 3 Li, the lithiation ...

Related Articles:

Synthesis, SAR, and antitumor properties of diamino-C, N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-β

[Gong, Baoqing; Hong, Feng; Kohm, Cory; Jenkins, Scott; Tulinsky, John; Bhatt, Rama; De Vries, Peter; Singer, Jack W.; Klein, Peter Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2303 - 2308]

Synthesis, SAR, and antitumor properties of diamino-C, N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-β

[Gong, Baoqing; Hong, Feng; Kohm, Cory; Jenkins, Scott; Tulinsky, John; Bhatt, Rama; De Vries, Peter; Singer, Jack W.; Klein, Peter Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2303 - 2308]

More Articles...