Cu (I)-mediated reductive amination of boronic acids with nitroso aromatics

Y Yu, J Srogl, LS Liebeskind

Index: Yu, Ying; Srogl, Jiri; Liebeskind, Lanny S Organic letters, 2004 , vol. 6, # 15 p. 2631 - 2634

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Citation Number: 45

Abstract

A mild method for the reductive amination of aryl boronic acids with nitroso aromatic compounds is reported. This CN bond formation is mediated by a stoichiometric amount of CuCl as both a catalyst and a reducing agent. Alternatively, 10% Cu (I)-3-methylsalicylate (CuMeSal) catalyzes the same reaction in the presence of either ascorbic acid or hydroquinone as the terminal reducing agent. Diarylamines bearing a variety of functional ...