Tetrahedron letters

Synthesis and binding property of an oligonucleotide containing tetrafluorophenoxazine

J Wang, KY Lin, MD Matteucci

Index: Wang, Jianying; Lin, Kuei-Ying; Matteucci, Mark D. Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8385 - 8388

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Citation Number: 17

Abstract

A tricyclic pyrimidine nucleoside analog, termed tetrafluorophenoxazine, has been synthesized and incorporated into an oligonucleotide. Tm analyses demonstrate that this analog is capable of enhanced recognition of both a complementary adenine and guanine within a DNA helix.