Development of benzothiazole 'click-on'fluorogenic dyes

J Qi, CH Tung

Index: Qi, Jianjun; Tung, Ching-Hsuan Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 320 - 323

Full Text: HTML

Citation Number: 19

Abstract

To study specific molecules in cells, precise labeling is the key. Ideally, the fluorescent reporter should only tag the interested targets. Fluorescent proteins co-expressed with targeted molecules have been widely used in studying cellular events, and the fluorescent signal makes the real time microscopic visualization of process possible. 1 and 2 However, the fluorescent proteins are large proteins, which could be too big for many applications. Small peptide tags have ...