First Synthesis of β-d-Gal f (1-4) GlcNAc, a Structural Unit Attached O-Glycosidically in Glycoproteins of Trypanosoma cruzi

C Gallo-Rodriguez, O Varela…

Index: Gallo-Rodriguez, Carola; Varela, Oscar; De Lederkremer, Rosa M. Journal of Organic Chemistry, 1996 , vol. 61, # 5 p. 1886 - 1889

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Citation Number: 46

Abstract

The glycobiology of galactofuranose is a topic of increasing interest. This monosaccharide is a constituent of polysaccharides and glycoconjugates from infectious bacteria, 1, 2 protozoa, 3, 4 and fungi, 5-7 while the mammal host does not biosynthesize glycoconjugates containing Galf. In particular, galactofuranose is a component of glycoinositol phospholipids, with anchor characteristics, isolated from Trypanosoma cruzi8, 9 and Leishmania species. ...