Synthesis

Stereoselective Synthesis of Tetrahydropyranyl Diarylheptanoids (-)-Centrolobine and (+)-Centrolobine

CR Reddy, PP Madhavi, S Chandrasekhar

Index: Reddy, Chada Raji; Madhavi, Pasupulety Phani; Chandrasekhar, Srivari Synthesis, 2011 , # 1 p. 123 - 126

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Citation Number: 3

Abstract

Abstract A versatile chiron approach to the tetrahydropyranyl diarylheptanoid natural products (-)-centrolobine and (+)-centrolobine has been described. The use of an aldol reaction followed by reductive etherification for the formation of tetrahydropyran ring is of importance.

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