Efficient copper-catalyzed intramolecular N-arylation for the synthesis of oxindoles
YH Jhan, TW Kang, JC Hsieh
Index: Jhan, Yu-Huei; Kang, Ting-Wei; Hsieh, Jen-Chieh Tetrahedron Letters, 2013 , vol. 54, # 9 p. 1155 - 1159
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Citation Number: 12
Abstract
An efficient copper-catalyzed intramolecular N-arylation was performed by using substituted 2-(2-bromoaryl) acetamide with a small amount of Cu2O and benzene-1, 2-diamine as catalytic system under aerobic conditions, which provided good to excellent yields of oxindoles with tolerance of a wide variety of substrates.
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