4-Arylazo-3, 5-diamino-1 H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects

V Kryštof, P Cankar, I Fryšová, J Slouka…

Index: Journal of Medicinal Chemistry, , vol. 49, # 22 p. 6500 - 6509

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Citation Number: 106

Abstract

... Journal of Medicinal ... DD1 5JJ, Scotland, United Kingdom, Laboratory of Experimental Medicine, Department of Pediatrics, Faculty of Medicine, Palacký University ... at the level of RNA polymerase II (RNAP-II) have recently attracted interest among medicinal chemists because of ...

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