Bioorganic & medicinal chemistry letters

Discovery and structure–activity relationships of small molecules that block the human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein–protein …

Z Wang, C Fraley, AR Mezo

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 5 p. 1253 - 1256

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Citation Number: 6

Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Chemical optimization of the initial hit compound 1 to compound 66 resulted in a 75-fold improvement in in vitro activity. ...