Intramolecular Ligation of Carbonyl Oxygen to Central Zinc in Synthetic Oligopeptide-Linked Zinc-Porphyrins.

H Tamiaki, A Kiyomori, K Maruyama

Index: Tamiaki; Kiyomori; Maruyama Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 9 p. 2478 - 2486

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Citation Number: 18

Abstract

Oligopeptide-linked zinc-porphyrins were prepared (oligopeptide=–Phe m–Ala n–OMe and porphyrin= 5, 15-diaryl-2, 3, 7, 8, 12, 13, 17, 18-octaethylporphyrin). 1 H NMR, IR, visible, and CD spectra of the synthetic molecule in a chlorinated methane (CDCl 3 or CH 2 Cl 2) showed that the carbonyl oxygen of the N-terminal amino acid of the linked peptide should ligate the central zinc metal in the molecule as the axial ligand to form a pentacoordinated ...

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