A Straightforward Synthesis of Pyrazolines and Pyrazoles: Palladium??Catalyzed Carbonylative Vinylation–Cyclocondensation Reactions of Aryl Halides

XF Wu, H Neumann, M Beller

Index: Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias European Journal of Organic Chemistry, 2011 , # 25 p. 4919 - 4924

Full Text: HTML

Citation Number: 8

Abstract

Abstract A novel consecutive one-pot synthesis of pyrazolines and pyrazoles starting from simple aryl halides, styrenes, carbon monoxide, and hydrazines has been established. Palladium-catalyzed carbonylative vinylation of aryl halides gave the corresponding chalcones, which are trapped in situ by addition of hydrazines.

Related Articles:

Palladium??Catalyzed Oxidative Carbonylative Coupling Reactions of Arylboronic Acids with Styrenes to Chalcones under Mild Aerobic Conditions

[Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias Chemistry - An Asian Journal, 2012 , vol. 7, # 2 p. 282 - 285]

BTISA-catalyzed Friedel–Crafts bimolecular cyclization of cinnamic acid under superelectrophilic solvation conditions

[Posternak, Anna G.; Garlyauskayte, Romute Yu.; Yagupolskii, Lev M. Journal of Fluorine Chemistry, 2010 , vol. 131, # 2 p. 274 - 277]

Reactions of unsaturated acid halides—IV11Part III. KM Johnston and JF Jones, J. Chem. Soc.(C), 814 (1969).: Competitive friedel-crafts acylations and alkylations of …

[Shotter,R.G. et al. Tetrahedron, 1978 , vol. 34, p. 741 - 746]

More Articles...