Synthesis of partially hydrogenated 1, 2, 4-triazoloquinazolines by condensation of 3, 5-diamino-1, 2, 4-triazole with aromatic aldehydes and dimedone
…, SM Desenko, VV Borodina, MG Shirobokova…
Index: Lipson; Desenko; Borodina; Shirobokova; Musatov Russian Journal of Organic Chemistry, 2005 , vol. 41, # 1 p. 114 - 119
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Citation Number: 39
Abstract
Abstract Three-component condensation of 3, 5-diamino-1, 2, 4-triazole with aromatic aldehydes and dimedone in dimethylformamide gives 2-amino-5-aryl-8, 8-dimethyl-5, 6, 7, 8, 9, 10-hexahydro [1, 2, 4] triazolo [3, 2-b] quinazolin-6-ones. The reaction of 3, 5-diamino- 1, 2, 4-triazole with dimedone in the absence of aldehyde involves dimethylformamide as one of the carbonyl components to afford 2-amino-8, 8-dimethyl-6, 7, 8, 9-tetrahydro [1, 2, ...
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