Efficient and economic halogenation of aryl amines via arenediazonium tosylate salts

YM Lee, ME Moon, V Vajpayee, VD Filimonov, KW Chi

Index: Lee, Young Min; Moon, Mi Eun; Vajpayee, Vaishali; Filimonov, Victor D.; Chi, Ki-Whan Tetrahedron, 2010 , vol. 66, # 37 p. 7418 - 7422

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Citation Number: 37

Abstract

Arenediazonium tosylate salts have been successfully employed as a new and efficient reagent in halogenation reactions. A novel and economic protocol has been developed for the bromination and chlorination of various anilines using arenediazonium tosylate salts. A wide variety of reaction conditions were studied in acetonitrile at either room temperature or 60° C in the presence or absence of catalyst with good to excellent yields. A surprising ...