A convenient reduction of highly functionalized aromatic carboxylic acids to alcohols with borane-THF and boron trifluoride-etherate

…, D Rodriguez, KE Sexton, J Zhang, HT Lee

Index: Chen; Iakovleva; Kesten; Magano; Rodriguez; Sexton; Zhang; Lee Organic Preparations and Procedures International, 2002 , vol. 34, # 6 p. 665 - 670

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Citation Number: 6

Abstract

The reduction of carboxylic acids to the corresponding alcohols has been performed with a variety of metal hydrides and complex metal hydrides, such as LiAM4, and its alkoxy derivatives,'NaBH,-Lewis acids? boranes, and combinations of borane-Lewis acids: The selective reduction of highly functionalized aromatic carboxylic acids with borane complexes is still not very well studied in the literature. During the recent synthesis of an important ...

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