An Efficient Synthesis of 2-[(4-Amino∼ 1, 2-dihyro-2-oxo-1-pyrimidinyl) methoxyi-l, 3-propanediyl-di-L-valinate an Anti-cytomegalovirus Agent

N Ghal, B Johnston, L Beauchamp…

Index: Nucleosides and Nucleotides, , vol. 14, # 7 p. 1591 - 1600

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Abstract

NUCLEOSlDES & NUCLEOTIDES, 14(7), 1591-1600 (1995) ... CHC02), 2.28-2.08 (2H, m, CaCH3)2), 0.97 (6H, d, C(C&)2 J=7 Hz), and 0.88 (6H, d, C(CH3)2, J=7 Hz ... To a mixture of N-CBZ-L-valine (14.4 g, 57 mmol), DCC (11.8 g, 57 mmol), 17 (5.0 g, 14 mmol) and 195 mL of ...