Synthesis and fate of o-carboxybenzophenones in the biosynthesis of aflatoxin

KM Henry, CA Townsend

Index: Henry, Kevin M.; Townsend, Craig A. Journal of the American Chemical Society, 2005 , vol. 127, # 10 p. 3300 - 3309

Full Text: HTML

Citation Number: 29

Abstract

o-Carboxybenzophenones have long been postulated to be intermediates in the oxidative rearrangement of anthraquinone natural products to xanthones in vivo. Many of these Baeyer-Villiger-like cleavages are believed to be carried out by cytochrome P450 enzymes. In the biosynthesis of the fungal carcinogen, aflatoxin, six cytochromes P450 are encoded by the biosynthetic gene cluster. One of these, AflN, is known to be involved in the conversion ...

Related Articles:

A simple and cost effective synthesis of chloromethyl methyl ether

[Journal of Organic Chemistry, , vol. 59, # 21 p. 6499 - 6500]

A simple and cost effective synthesis of chloromethyl methyl ether

[Journal of Organic Chemistry, , vol. 59, # 21 p. 6499 - 6500]

Discovery and optimization of new chromium catalysts for ethylene oligomerization and polymerization aided by high-throughput screening

[Journal of the American Chemical Society, , vol. 127, # 31 p. 11037 - 11046]

Simple, Rapid Procedure for the Synthesis of Chloromethyl Methyl Ether and Other Chloro Alkyl Ethers1

[Journal of Organic Chemistry, , vol. 70, # 23 p. 9618 - 9621]

Simple, Rapid Procedure for the Synthesis of Chloromethyl Methyl Ether and Other Chloro Alkyl Ethers1

[Journal of Organic Chemistry, , vol. 70, # 23 p. 9618 - 9621]

More Articles...